Dr. D’Amore’s research seeks to couple a mechanistic understanding of the relationship between scaffolds micro-structure, mechanics, and endogenous tissue growth with the development of novel biomaterials for tissue engineering strategies. The focus of his research is upon unmet clinical needs in cardiovascular diseases. Areas of interest include: quantitative histology and biomaterials micro-structure image-based analysis, structural modeling strategies to guide tissue engineering scaffold fabrication, mechanical and topological conditioning for tissue elaboration, development of cardiac restrain devices, vascular grafts and engineered heart valves. Recent research efforts combine material processing and microgravity to enhance tissue elaboration in cardiovascular tissue surrogates.
